“There have been several exciting developments since the last Reaxys update, notably the integration of PubChem into Reaxys, the move to bi-weekly content updates and more. Any structure searches done in Reaxys are now run across the PubChem compounds at the same time and in the same interface – increasing the number of compounds being searched which is valuable for any prior-art activities and researchers can now generate synthetic pathways for PubChem compounds not in Reaxys via Reaxys’ similarity searching.”